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https://cordycepssinensis.org/ | |
Title: | https://cordycepssinensis.org/ |
URL: | https://cordycepssinensis.org/ |
Description: | Certain varieties of Cordyceps grow parasitically on the caterpillars of particular moths. Some species of Cordyceps are called “winter worm” (these mushrooms grow on a caterpillar, after killing it and filling it with mycelium) and “summer grass”. These endangered mushrooms only occurs in the high mountains (the Qinghai-Tibetan Plateau) in southwestern China and Tibet. Fortunately, the mycelia of Cordyceps sinensis can also be grown domestically, using a substrate such as rice. Researchers have found that the mycelia of domestic Cordyceps sinensis varieties contain the same pharmacological components and medicinal properties as the original, wild Cordyceps. This also applies to (domestic) mycelia of Cordyceps militaris. The risk of cognitive decline and dementia increases with age. Researchers have found a significant increase in the activity of antioxidant enzymes (glutathione peroxidase, superoxidedismutase, catalase), whose activity was decreased by the aging process. The (ultra) structure of the hippocampus, a brain area in which degenerative changes had occurred, increased strongly by supplementation with Cordyceps. The research suggests that Cordyceps sinensis helps keep the brains healthy with age, both structurally and functionally, partly by improving the antioxidant status. Since fatigue and depression are closely linked, researchers wanted to know if Cordyceps sinensis has an antidepressant effect. They found confirmation of this hypothesis in a widely used animal model for depression (tail suspension test), in which cordyceps extract (obtained by supercritical fluid extraction with CO2) a significant antidepressant effect showed. The researchers found that the antidepressant activity partly based on influencing the adrenergic * and dopaminergic * systems (and not the serotonergic system). According to the “monoamine hypothesis” monoamines * (norepinephrine, dopamine, serotonin) play an important role in the development of depression symptoms. |